Low Binding Microcentrifuge Tubes Screw Cap CLEARLine®

CLEARLine® Low Binding Screw Cap Microtubes are designed for laboratories that need reliable recovery and secure storage of valuable biological samples, especially when working with proteins, DNA, RNA or other nucleic acids at low concentrations.

Sample loss caused by binding to tube surfaces can affect the accuracy and reproducibility of sensitive workflows. Biosigma Low Binding microtubes help minimize this risk by reducing interactions between analytes and the tube wall, supporting better recovery during handling, centrifugation, preparation and storage.

The range includes Protein Low Binding microtubes for biochemistry and proteomics applications and DNA Low Binding microtubes for molecular biology workflows such as nucleic acid amplification and PCR. Made from medical-grade polypropylene, the tubes are produced without intentional addition of PFAS during the production process. They feature a secure screw cap, graduated markings and an engraved writing area for easy identification. Available in 1.5 ml and 2 ml capacities, they are suitable for use with various microcentrifuges, racks and laboratory storage systems.

The tubes are sterilized by beta irradiation (SAL 10⁻⁶), and each batch is certified free from human and bacterial DNA, DNase, RNase, endotoxins and PCR inhibitors, making them suitable for demanding laboratory applications where sample integrity is essential.

CLEARLine® Low Binding Screw Cap Microtubes are available in two dedicated versions: Protein Low Binding for protein recovery and DNA Low Binding for nucleic acid recovery.
Both versions are made without intentional addition of PFAS during the production process and designed to reduce sample loss during handling and storage, especially when working with low-concentration samples.

Protein Low Binding:
Protein Low Binding Screw Cap Microtubes are designed to minimize protein adsorption to tube surfaces, supporting maximum sample recovery even when working with low concentrations or small volumes.
They are the ideal solution for the preparation, analysis, and long-term storage of antibodies, enzymes, and other valuable protein substances. They are particularly suitable for the field of proteomics and for numerous other routine applications where maximizing sample recovery is crucial.

DNA Low Binding:
DNA Low Binding Screw Cap Microtubes are designed to minimize nucleic acid adsorption to tube surfaces, reducing potential sample loss, especially when working with low concentrations.
They are the ideal solution for both the preparation and long-term storage of nucleic acids, amplification products, plasmids, PCR reagents, and buffer solutions.

Protein Low Binding:

• Low binding surface designed to minimize protein adsorption and improve sample recovery
• Ideal for low-concentration protein samples and small volumes
• Secure screw cap closure for reliable sample handling and storage
• Available in 1.5 ml and 2 ml capacities, with conical or self-standing bottom
• Graduated tube with engraved writing area for easy sample identification
• High centrifugation resistance, up to 25,000 × g
• Temperature range from -85°C to +121°C
• Autoclavable at +121°C for 20 minutes
• Medical-grade polypropylene tubes and polyethylene caps
• Sterilized by beta irradiation (SAL 10⁻⁶)
• Certified free from human and bacterial DNA, DNase, RNase, endotoxins and PCR inhibitors
• Metal free

DNA Low Binding

• Low binding surface designed to minimize DNA and RNA adsorption and improve nucleic acid recovery
• Ideal for low-concentration nucleic acid samples and small volumes
• Secure screw cap closure for reliable sample handling and storage
• Available in 1.5 ml and 2 ml capacities, with conical or self-standing bottom
• Graduated tube with engraved writing area for easy sample identification
• High centrifugation resistance, up to 25,000 × g
• Temperature range from -85°C to +121°C
• Autoclavable at +121°C for 20 minutes
• Medical-grade polypropylene tubes and polyethylene caps
• Sterilized by beta irradiation (SAL 10⁻⁶)
• Certified free from human and bacterial DNA, DNase, RNase, endotoxins and PCR inhibitors
• Metal free

Protein Low Binding:

• Protein extraction, purification and sample preparation
• Protein quantification and analysis
• Enzyme handling and storage
• Antibody preparation and storage
• Immunoprecipitation and ELISA
• Western blotting
• Mass spectrometry and proteomics
• Long-term storage of protein samples
• Biochemistry and biotechnology research

DNA Low Binding:

• DNA and RNA extraction and purification
• PCR and quantitative PCR (qPCR)
• DNA amplification and sequencing
• Cloning and plasmid preparation
• Next-generation sequencing (NGS) library preparation
• DNA methylation analysis
• Storage of nucleic acids and amplification products
• Preparation and storage of PCR reagents and buffer solutions
• Molecular biology and genetics research